Article
Mitochondrial DNA sequence alterations observed between blood and buccal cells within the same individuals having betel quid (BQ)-chewing habit.
Forensic science international - 27 Jan 2006
Pai Chung-Yen, Hsieh Ling-Ling, Lee Tzu-Cheng, Yang Shi-Bing, Linville Jason, Chou Su-Lien, Yang Chiou-Herr
Abstract excerpt
There are hundreds of millions of betel quid (BQ) lovers widely spreading around the world. Compositions in BQ may generate reactive oxygen species, which would induce DNA damage. However, oral epithelial cells as well as blood have often been used as reference samples in comparison with the mitochondrial DNA (mtDNA) sequence of hairs. The main purpose of this study was to investigate the extent of mtDNA sequence...
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