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Article

Effects of a alpha 2C-adrenoreceptor gene polymorphism on neural responses to facial expressions in depression.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Aug 2006

Neumeister Alexander, Drevets Wayne C, Belfer Inna, Luckenbaugh David A, Henry Shannan, Bonne Omer, Herscovitch Peter, Goldman David, Charney Dennis S

Abstract excerpt

Alterations in processing of emotionally salient information have been reported in individuals with major depressive disorder (MDD). Evidence suggests a role for noradrenaline in the regulation of a cortico-limbic-striatal circuit that has also been implicated in the pathophysiology of MDD. Herein, we studied the physiological consequences of a common coding polymorphism of the gene for the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16407897
DOI: 10.1038/sj.npp.1301010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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