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Article

Cannabinoid receptor 1 (CNR1) gene: impact on antidepressant treatment response and emotion processing in major depression.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Oct 2008

Domschke Katharina, Dannlowski Udo, Ohrmann Patricia, Lawford Bruce, Bauer Jochen, Kugel Harald, Heindel Walter, Young Ross, Morris Phillip, Arolt Volker, Deckert Jürgen, Suslow Thomas, Baune Bernhard T

Abstract excerpt

The endocannabinoid system has been implicated in the pathogenesis of depression and anxiety, the mediation of antidepressant drug effects in animal models and the neurobiology of emotion processing in healthy volunteers. Therefore, the impact of cannabinoid receptor 1 gene (CNR1) variants rs1049353 and rs12720071 on antidepressant treatment response was evaluated in 256 Caucasian patients with Major Depression....

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Share to Antidepressive Agents
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Share to Receptor, Cannabinoid, CB1

Source

Identifiers

PMID: 18579347
DOI: 10.1016/j.euroneuro.2008.05.003

Genes

CNR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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