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Article

FHL1 regulates myoblast differentiation and autophagy through its interaction with LC3

21 Oct 2019

Abstract excerpt

Four and a half LIM domain protein 1 (FHL1) belongs to the FHL protein family and is predominantly expressed in skeletal and cardiac muscle. FHL1 acts as a scaffold during sarcomere assembly and plays a vital role in muscle growth and development. Autophagy is key to skeletal muscle development and regeneration, with its dysfunction associated with a range of muscular pathologies and disorders. In this study, we...

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PMID: 31637727
DOI: 10.1002/jcp.29345

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