Article
Effect of IL-1β and IL-1RN polymorphisms in carcinogenesis of the gastric mucosa in patients infected with Helicobacter pylori in Algeria.
The Libyan journal of medicine - 1 Jan 2016
Drici Amine El-Mokhtar, Moulessehoul Soraya, Tifrit Abdelkarim, Diaf Mustapha, Turki Douidi Kara, Bachir Meryem, Tou Abdenacer
Abstract excerpt
BACKGROUND: Infection with Helicobacter pylori is considered a potential risk of developing gastric cancer in association with contributing host genetic factor. IL-1β and IL-1RN polymorphisms appear to maintain and promote Helicobacter pylori infection and to stimulate neoplastic growth of the gastric mucosa. OBJECTIVE AND METHODS: In order to elucidate the effect of these polymorphisms in combination with...
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