Article
Interleukin-1B (IL-1B) polymorphisms and gastric mucosal levels of IL-1beta cytokine in Korean patients with gastric cancer.
International journal of cancer - 10 Apr 2005
Chang Young-Woon, Jang Jae-Young, Kim Nam-Hoon, Lee Jae Won, Lee Hyo Jung, Jung Woon Won, Dong Seok-Ho, Kim Hyo-Jong, Kim Byung-Ho, Lee Joung-Il, Chang Rin
Abstract excerpt
Interleukin-1B and IL-1 receptor antagonist gene polymorphisms are associated with an increased risk of gastric cancer (GC) in Caucasian populations. However, recent studies could not find any association between IL-1B-511T polymorphism and the risk of GC in Asians. We tested for an association between IL-1 loci polymorphisms with increased gastric mucosal levels of IL-1beta and an increased risk of developing GC...
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