Analysis of the Influence of Interleukin-1β Gene Polymorphism on Gastric Inflammatory Response and Precancerous Lesions Development in Patients with Functional Dyspepsia.

doi:10.1080/08820139.2019.1710532

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Article

Analysis of the Influence of Interleukin-1β Gene Polymorphism on Gastric Inflammatory Response and Precancerous Lesions Development in Patients with Functional Dyspepsia.

Immunological investigations - 1 Jul 2020

Rech Tássia Flores, Mazzoleni Luiz Edmundo, Mazzoleni Felipe, Francesconi Carlos Fernando de Magalhães, Sander Guilherme Becker, Michita Rafael Tomoya, Nabinger Débora Dreher, de Bona Laura Renata, Milbradt Tobias Cancian, Ott Eduardo André, Breyer Helenice Pankowski, Haas Gelline Maria, Canevese Ane Paula, Stifft Jonathas, Simon Daniel

Abstract excerpt

The present study aimed to evaluate the influence of the IL1B -31C/T polymorphism on gastric inflammatory response and precancerous lesions development - atrophic gastritis (AG) and intestinal metaplasia (IM) - in patients positive for Helicobacter pylori infection with functional dyspepsia (FD). The diagnosis of FD followed the Rome III criteria, and the H. pylori infection was evaluated by urease test and...

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PMID: 31909646
DOI: 10.1080/08820139.2019.1710532

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