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Article

Stochastic imprinting in the progeny of Dnmt3L−/− females

10 Jan 2006

Abstract excerpt

The cis-acting regulatory sequences of imprinted genes are subject to germline-specific epigenetic modifications, the imprints, so that this class of genes is exclusively expressed from either the paternal or maternal allele in offspring. How genes are differentially marked in the germlines remains largely to be elucidated. Although the exact nature of the mark is not fully known, DNA methylation [at...

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PMID: 16403808
DOI: 10.1093/hmg/ddi475

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