Article
Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy.
Laboratory investigation; a journal of technical methods and pathology - 1 Jul 2008
Majewski Tadeusz, Lee Sangkyou, Jeong Joon, Yoon Dong-Sup, Kram Andrzej, Kim Mi-Sook, Tuziak Tomasz, Bondaruk Jolanta, Lee Sooyong, Park Weon-Seo, Tang Kuang S, Chung Woonbok, Shen Lanlan, Ahmed Saira S, Johnston Dennis A, Grossman H Barton, Dinney Colin P, Zhou Jain-Hua, Harris R Alan, Snyder Carrie, Filipek Slawomir, Narod Steven A, Watson Patrice, Lynch Henry T, Gazdar Adi, Bar-Eli Menashe, Wu Xifeng F, McConkey David J, Baggerly Keith, Issa Jean-Pierre, Benedict William F, Scherer Steven E, Czerniak Bogdan
Abstract excerpt
The search for the genomic sequences involved in human cancers can be greatly facilitated by maps of genomic imbalances identifying the involved chromosomal regions, particularly those that participate in the development of occult preneoplastic conditions that progress to clinically aggressive invasive cancer. The integration of such regions with human genome sequence variation may provide valuable clues about...
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