Genome-widely significant evidence of linkage of schizophrenia to chromosomes 2p24.3 and 6q27 in an SNP-Based analysis of Korean families.

doi:10.1002/ajmg.b.30884

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Article

Genome-widely significant evidence of linkage of schizophrenia to chromosomes 2p24.3 and 6q27 in an SNP-Based analysis of Korean families.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jul 2009

Hong Kyung Sue, Won Hong-Hee, Cho Eun-Young, Jeun Hyun Ok, Cho Sang-Seon, Lee Yu-Sang, Park Dong Yeon, Jang Yong Lee, Choi Kyeong-Sook, Lee Dongsoo, Kim Min-Ji, Kim Seonwoo, Han Wou Sang, Kim Jong-Won

Abstract excerpt

The present study reports the results of a genome-wide SNP linkage scan for schizophrenia in the Korean population. Fifty-six multiplex schizophrenia families were analyzed. Clinical evaluations on all subjects were consistently performed by raters in a single research team. Multipoint non-parametric linkage analysis was performed, and empirical simulations were generated to determine genome-wide significance....

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PMID: 18980222
DOI: 10.1002/ajmg.b.30884

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