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Article

Mouse imprinting defect mutations that model Angelman syndrome.

Genesis (New York, N.Y. : 2000) - 1 Jan 2006

Wu Mei-Yi, Chen Ken-Shiung, Bressler Jan, Hou Aihua, Tsai Ting-Fen, Beaudet Arthur L

Abstract excerpt

Prader-Willi syndrome (PWS) and Angelman syndrome (AS) are neurobehavioral disorders resulting from deficiency of imprinted gene expression from paternal or maternal chromosome 15q11-15q13, respectively. In humans, expression of the imprinted genes is under control of a bipartite cis-acting imprinting center (IC). Families with deletions causing PWS imprinting defects localize the PWS-IC to 4.3 kb overlapping...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16397868
DOI: 10.1002/gene.20179

Genes

SNRPN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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