Article
Correlation of myc expression with the growth-arrested and transformed phenotypes in hybrids between a T lymphoma and an antigen-responsive T-cell line.
International journal of cancer - 30 Jul 1992
Kubota K, Imreh S, Katoh H, Babonits M, Wiener F
Abstract excerpt
Fusion of the YACUT lymphoma cell line with the Mls-1a-antigen-specific non-tumorigenic T-cell line G4 produced growth-arrested hybrids that could be induced to proliferate in the presence of Mls-1a antigen. Prolonged growth of such hybrids by repeated antigenic stimulation resulted in the appearance of autonomously growing hybrid lines. Of the 4 antigen-independent hybrid clones, I was weakly tumorigenic (25%...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.