Article
Correlation of myc expression with the growth-arrested and transformed phenotypes in hybrids between a T lymphoma and an antigen-responsive T-cell line.
International journal of cancer - 30 Jul 1992
Kubota K, Imreh S, Katoh H, Babonits M, Wiener F
Abstract excerpt
Fusion of the YACUT lymphoma cell line with the Mls-1a-antigen-specific non-tumorigenic T-cell line G4 produced growth-arrested hybrids that could be induced to proliferate in the presence of Mls-1a antigen. Prolonged growth of such hybrids by repeated antigenic stimulation resulted in the appear...
Topics
- Animals
- Cell Division
- Cell Fusion
- Cell Line
- Cell Line, Transformed
- Chromosome Banding
- Chromosome Mapping
- Gene Expression
- Genes, myc
- Glucose-6-Phosphate Isomerase
- Hybrid Cells
- Karyotyping
- Lymphoma, T-Cell
- Mice
- Mice, Inbred Strains
- Phenotype
- RNA, Messenger
- T-Lymphocytes