Article
Studies on the relationship between chromosome No15 and the biological characteristics of malignant transformed Syrian hamster fibroblast cell lines.
Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan, Chung-kuo hsieh ho i k'o ta hsueh hsueh pao - 1 Jan 1990
Li S, Liu B, Xu D
Abstract excerpt
During the course of malignant transformation of mammalian cells in vitro, a regular variation in chromosome number and structure is usually found. In order to elucidate the relationship between chromosomal changes and malignant expression, we isolated five clones from a malignant transformed Syrian hamster fibroblast cell line and analysed their biological characteristics, as well as chromosomal changes. A...
Topics
- Animals
- Cell Line, Transformed
- Chromosome Deletion
- Cricetinae
- Fibroblasts
- Fibrosarcoma
- Gene Expression Regulation, Neoplastic
- Lung
- Mesocricetus
- Methylnitronitrosoguanidine
