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Article

Association between multidrug resistance 1 (MDR1) gene polymorphisms and therapeutic response to bromperidol in schizophrenic patients: a preliminary study.

Progress in neuro-psychopharmacology & biological psychiatry - 1 Mar 2006

Yasui-Furukori Norio, Saito Manabu, Nakagami Taku, Kaneda Ayako, Tateishi Tomonori, Kaneko Sunao

Abstract excerpt

The drug-transporting P-glycoprotein transports drugs against a concentration gradient across the blood-brain barrier back into the plasma and thereby reduces the bioavailability in the brain. Polymorphisms in the MDR1 gene regulating P-glycoprotein expression can be associated with differences in drug disposition in the brain. The present study was therefore designed to examine whether the major polymorphisms of...

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Identifiers

PMID: 16386826
DOI: 10.1016/j.pnpbp.2005.06.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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