Frequency of "Poor Transporter" Phenotype Among Patients with Mental Disorders: Pilot Study

Abstract excerpt

The problem of psychopharmacotherapy safety is actively studied, but remains unresolved, despite the development of new generations of psychotropic drugs (PDs). Neurotoxic adverse drug reactions (ADRs) are one of the leading causes of pseudo-resistance of mental disorders and patient disability. The development of neurotoxic ADRs is genetically determined, and caused by a slowdown in the efflux of PDs from the bra...

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• Drug Transport and Resistance Mechanisms
• Gastroesophageal reflux and treatments
• Pharmacological Effects and Toxicity Studies

Identifiers and source

Literature Corpus work

cbf0315f-f636-5be9-a381-6190e9db8717

DOI

10.52667/2712-9179-2024-4-3-37-44