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Article

O6-alkylguanine-DNA alkyltransferase gene polymorphisms and the risk of primary lung cancer.

Molecular carcinogenesis - 1 Apr 2006

Chae Myung Hwa, Jang Jin-Sung, Kang Hyo-Gyoung, Park Jae Hyung, Park Jung Min, Lee Won Kee, Kam Sin, Lee Eung Bae, Son Ji-Woong, Park Jae Yong

Abstract excerpt

O6-alkylguanine-DNA alkyltransferase (AGT) plays an important role in the repair of O6-alkylguanine adducts, which are major mutagenic lesions produced by environmental carcinogens. Polymorphisms in the AGT gene may affect the capacity to repair DNA damage and thereby have influence on individual's susceptibility to smoking-related cancer. To test this hypothesis, we investigated the potential association of AGT...

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Source

Identifiers

PMID: 16385589
DOI: 10.1002/mc.20171

Genes

AGT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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