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Article

Glu346Lys polymorphism in the methyl-CpG binding domain 4 gene and the risk of primary lung cancer.

Japanese journal of clinical oncology - 1 Aug 2006

Shin Moo Chul, Lee Su Jeong, Choi Jin Eun, Cha Sung Ick, Kim Chang Ho, Lee Won Kee, Kam Sin, Kang Young Mo, Jung Tae Hoon, Park Jae Yong

Abstract excerpt

BACKGROUND: Methyl-CpG binding domain 4 (MBD4) protein functions as a DNA repair enzyme and minimizes mutations at 5-methylcytosine. Polymorphisms in the DNA repair gene MBD4 may be associated with differences in DNA repair capacity and thereby influence an individual's susceptibility to lung cancer. To test this hypothesis, we examined the potential association between the MBD4 Glu346Lys polymorphism and the...

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Source

Identifiers

PMID: 16803845
DOI: 10.1093/jjco/hyl055

Genes

MBD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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