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Article

DNMT3B polymorphisms and risk of primary lung cancer.

Carcinogenesis - 1 Feb 2005

Lee Su Jeong, Jeon Hyo-Sung, Jang Jin-Sung, Park Sun Ha, Lee Ga Young, Lee Byung-Heon, Kim Chang Ho, Kang Young Mo, Lee Won Kee, Kam Sin, Park Rang Woon, Kim In-San, Cho Young Lae, Jung Tae Hoon, Park Jae Yong

Abstract excerpt

DNA-methyltransferase-3B (DNMT3B) plays an important role in the generation of aberrant methylation in carcinogenesis. Polymorphisms and haplotypes of the DNMT3B gene may influence DNMT3B activity on DNA methylation, thereby modulating the susceptibility to lung cancer. To test this hypothesis, we investigated the association of the -283T > C (from exon 1A transcription start site) and -579G > T (from exon 1B...

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Identifiers

PMID: 15528220
DOI: 10.1093/carcin/bgh307

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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