Article
Study of the association of serotonin transporter triallelic 5-HTTLPR and STin2 VNTR polymorphisms with lithium prophylaxis response in bipolar disorder.
Psychiatric genetics - 1 Apr 2013
Tharoor Hema, Kotambail Ananthapadmanabha, Jain Sanjeev, Sharma Podila Satya Venkata Narasimha, Satyamoorthy Kapaettu
Abstract excerpt
The 5-hydroxy tryptamine transporter (5-HTT) gene has been previously implicated in lithium response, but the roles of the triallelic 5-HTT linked promoter region (5-HTTLPR) and variable number tandem repeats in the second intron [serotonin transporter intron 2 (STin2)] have not been reported. We examined these polymorphisms in 122 patients with bipolar I disorder, among which 49 patients were classified as good...
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