Article
Interaction of OGG1 Ser326Cys polymorphism with cigarette smoking in head and neck squamous cell carcinoma.
Molecular carcinogenesis - 1 May 2006
Hashimoto Tomoko, Uchida Kenichiro, Okayama Naoko, Imate Yuji, Suehiro Yutaka, Hamanaka Yuichiro, Ueyama Yoshiya, Yamashita Hiroshi, Hinoda Yuji
Abstract excerpt
Recent molecular epidemiological studies have demonstrated that the human oxoguanine glycosylase 1 (OGG1) gene polymorphism may be associated with various cancers. To determine whether the OGG1 Ser326Cys polymorphism interacts with clinicopathological parameters including smoking and alcohol intake in head and neck squamous cell carcinoma (HNSCC), DNA samples from 192 patients with primary HNSCC were genotyped...
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