Article
The Cys326 allele of the 8-oxoguanine DNA N-glycosylase 1 gene as a risk factor in smoking- and drinking-associated larynx cancer.
The Tohoku journal of experimental medicine - 1 Dec 2009
Pawlowska Elzbieta, Janik-Papis Katarzyna, Rydzanicz Malgorzata, Zuk Karolina, Kaczmarczyk Dariusz, Olszewski Jurek, Szyfter Krzysztof, Blasiak Janusz, Morawiec-Sztandera Alina
Abstract excerpt
Tobacco smoke-related products and ethanol would induce oxidative modifications to the DNA bases, thereby contributing to larynx cancer. Human 8-oxoguanine DNA N-glycosylase 1 (hOGG1) deals with oxidative DNA damage, and the base changes in the hOGG1 gene may alter the susceptibility of the human...
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