Article
hOGG1 Ser326Cys polymorphism is associated with risk of bladder cancer in a Chinese population: a case-control study.
Cancer science - 1 Jul 2012
Ma Lan, Chu Haiyan, Wang Meilin, Shi Danni, Zhong Dongyan, Li Pu, Tong Na, Yin Changjun, Zhang Zhengdong
Abstract excerpt
Human oxoguanine glycosylase 1 (hOGG1) is a DNA repair enzyme, which plays important roles in the base excision repair (BER) pathway. Several studies reported a common polymorphism Ser326Cys (rs1052133) in hOGG1, which conferred the susceptibility of bladder cancer. We hypothesized that the polymorphism is associated with risk of bladder cancer in a Chinese population. In a case-control study of 1050...
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