Article
Uncommon V599E BRAF mutations in Japanese patients with lung cancer.
The Journal of surgical research - 15 Jun 2006
Sasaki Hidefumi, Kawano Osamu, Endo Katsuhiko, Suzuki Eriko, Haneda Hiroshi, Yukiue Haruhiro, Kobayashi Yoshihiro, Yano Motoki, Fujii Yoshitaka
Abstract excerpt
BACKGROUND: Recently, somatic mutations of the epidermal growth factor receptor (EGFR) gene and Braf gene were found in patients with lung cancer. These mutations might be correlated with a clinical response to molecular target therapy. Although a few Caucasian lung cancer patients harbored BRAF mutations, there have been no reports about the BRAF mutation in Japanese patients with lung cancer. MATERIALS AND...
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