Article
Clinical, pathologic, and biologic features associated with BRAF mutations in non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Aug 2013
Cardarella Stephanie, Ogino Atsuko, Nishino Mizuki, Butaney Mohit, Shen Jeanne, Lydon Christine, Yeap Beow Y, Sholl Lynette M, Johnson Bruce E, Jänne Pasi A
Abstract excerpt
PURPOSE: BRAF mutations are found in a subset of non-small cell lung cancers (NSCLC). We examined the clinical characteristics and treatment outcomes of patients with NSCLC harboring BRAF mutations. EXPERIMENTAL DESIGN: Using DNA sequencing, we successfully screened 883 patients with NSCLC for BRAF mutations between July 1, 2009 and July 16, 2012. Baseline characteristics and treatment outcomes were compared...
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