Article
A BRAF new world.
Critical reviews in oncology/hematology - 1 Aug 2020
Frisone Daniele, Friedlaender Alex, Malapelle Umberto, Banna Giuseppe, Addeo Alfredo
Abstract excerpt
BRAF is a rare targetable mutation in non-small-cell lung cancer (NSCLC). Emerging evidence underlines that, rather than a single point mutation, BRAF genes present with a wide array of mutations, essentially in lung adenocarcinoma. Different BRAF mutations have divergent clinical and therapeutic implications, with a particular distinction between V600E and non-V600E mutations. The latter are at least as frequent...
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