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Article

Epidermal development and wound healing in matrix metalloproteinase 13-deficient mice.

The Journal of investigative dermatology - 1 Feb 2006

Hartenstein Bettina, Dittrich Bernd Thilo, Stickens Dominique, Heyer Babette, Vu Thiennu H, Teurich Sibylle, Schorpp-Kistner Marina, Werb Zena, Angel Peter

Abstract excerpt

Degradation of the extracellular matrix, which is an indispensable step in tissue remodelling processes such as embryonic development and wound healing of the skin, has been attributed to collagenolytic activity of members of the matrix metalloproteinase family (MMPs). Here, we employed mmp13 knockout mice to elucidate the function of MMP13 in embryonic skin development, skin homeostasis, and cutaneous wound...

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Topics

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Share to Collagenases
Share to Epidermal Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epidermis

Share to Matrix Metalloproteinase 13

Share to Matrix Metalloproteinase 8

Share to Neovascularization, Physiologic

Share to Wound Healing

Source

Open in PubMed Open full text

Identifiers

PMID: 16374453
DOI: 10.1038/sj.jid.5700084
PMCID: PMC2767339

Genes

MMP13
MMP8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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