Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic overlap between MMP-13 and the plasminogen activation system during wound healing in mice.

PloS one - 4 Feb 2011

Juncker-Jensen Anna, Lund Leif R

Abstract excerpt

BACKGROUND: Proteolytic degradation of extracellular matrix is a crucial step in the healing of incisional skin wounds. Thus, healing of skin wounds is delayed by either plasminogen-deficiency or by treatment with the broad-spectrum metalloproteinase (MP) inhibitor Galardin alone, while the two perturbations combined completely prevent wound healing. Both urokinase-type plasminogen activator and several matrix...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Matrix Metalloproteinase 13
Share to Mice, Knockout
Share to Plasminogen

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Plasminogen Activators

Share to Skin Diseases

Share to Survival

Share to Urokinase-Type Plasminogen Activator

Share to Wound Healing

Source

Open in PubMed Open full text

Identifiers

PMID: 21326869
DOI: 10.1371/journal.pone.0016954
PMCID: PMC3033913

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic overlap between MMP-13 and the plasminogen activation system during wound healing in mice.PMID 21326869Read ↗

SERPINE1: A Molecular Switch in the Proliferation-Migration Dichotomy in Wound-“Activated” KeratinocytesSemantic proximity Read ↗

Development and disease in proteinase-deficient mice: role of the plasminogen, matrix metalloproteinase and coagulation system.Semantic proximity Read ↗

Epidermal development and wound healing in matrix metalloproteinase 13-deficient mice.Semantic proximity Read ↗

Mice deficient in urokinase-type plasminogen activator have delayed healing of tympanic membrane perforations.Semantic proximity Read ↗

The role of plasminogen in angiogenesis in vivo.Semantic proximity Read ↗

MMP-13 Plays a Role in Keratinocyte Migration, Angiogenesis, and Contraction in Mouse Skin Wound HealingSemantic proximity Read ↗

Transforming growth factor-beta3 affects plasminogen activator inhibitor-1 expression in fetal mice and modulates fibroblast-mediated collagen gel contraction.Semantic proximity Read ↗

Urokinase-type plasminogen activator and its receptor synergize to promote pathogenic proteolysis.Semantic proximity Read ↗

Transforming Growth Factor-Beta and Urokinase-Type Plasminogen Activator: Dangerous Partners in Tumorigenesis—Implications in Skin CancerSemantic proximity Read ↗

Diversity and functional evolution of the plasminogen activator system.Semantic proximity Read ↗

Structure and function of the plasminogen/plasmin system.Semantic proximity Read ↗

Plasminogen mediates the pathological effects of urokinase-type plasminogen activator overexpression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.