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Article

Matrix metalloproteinases and the regulation of tissue remodelling.

Nature reviews. Molecular cell biology - 1 Mar 2007

Page-McCaw Andrea, Ewald Andrew J, Werb Zena

Abstract excerpt

Matrix metalloproteinases (MMPs) were discovered because of their role in amphibian metamorphosis, yet they have attracted more attention because of their roles in disease. Despite intensive scrutiny in vitro, in cell culture and in animal models, the normal physiological roles of these extracellular proteases have been elusive. Recent studies in mice and flies point to essential roles of MMPs as mediators of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17318226
DOI: 10.1038/nrm2125
PMCID: PMC2760082

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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