Article
Common neuropeptide Y2 receptor gene variant is protective against obesity among Swedish men.
International journal of obesity (2005) - 1 Mar 2006
Lavebratt C, Alpman A, Persson B, Arner P, Hoffstedt J
Abstract excerpt
BACKGROUND: Gut hormones and their receptors are considered important in the control of feeding behavior. The gut hormone peptide-YY (PYY) has anorexic effects via the inhibitory neuropeptide Y2 receptor (Y2R) highly expressed in orexigenic NPY/AGRP neurons within the arcuate nucleus, a major integrator of appetite control in the hypothalamus. DESIGN: Genetic case-control association study of single nucleotide...
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