Article
Peptidoglycan recognition proteins Pglyrp3 and Pglyrp4 are encoded from the epidermal differentiation complex and are candidate genes for the Psors4 locus on chromosome 1q21.
Human genetics - 1 Mar 2006
Sun Chao, Mathur Punam, Dupuis Josée, Tizard Rich, Ticho Barry, Crowell Tom, Gardner Humphrey, Bowcock Anne M, Carulli John
Abstract excerpt
Psoriasis is a common inflammatory skin disease caused by genetic and environmental factors, including bacterial and viral infections. Since the skin is in constant contact with commensal and pathogenic microorganisms, we examined well-supported psoriasis genetic linkage intervals to identify genes encoding innate immune pattern recognition proteins that may play a role in pathogenesis. Two peptidoglycan...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.