Article
Association of skin barrier genes within the PSORS4 locus is enriched in Singaporean Chinese with early-onset psoriasis.
The Journal of investigative dermatology - 1 Mar 2009
Chen Huijia, Toh Terry K L, Szeverenyi Ildiko, Ong Rick T H, Theng Colin T S, McLean W H Irwin, Seielstad Mark, Lane E Birgitte
Abstract excerpt
Psoriasis (OMIM#177900) is a common polygenic skin disorder affecting approximately 2% of the northern European population and 0.1% of the Han Chinese. Psoriasis patients suffer from chronic skin inflammation, manifested by erythematous scaly lesions. PSORS1-PSORS9 have been confirmed as psoriasis susceptibility loci in independent genetic studies on predominantly Caucasian populations, with psoriasis...
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