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Article

Kinase Cak1 functionally interacts with the PAF1 complex and phosphatase Ssu72 via kinases Ctk1 and Bur1.

Molecular genetics and genomics : MGG - 1 Feb 2006

Ganem Carine, Miled Chaouki, Facca Céline, Valay Jean-Gabriel, Labesse Gilles, Ben Hassine Samia, Mann Carl, Faye Gérard

Abstract excerpt

Protein kinases orthologous with Cak1 of Saccharomyces cerevisiae (ScCak1) appear specific to ascomycetes. ScCak1 phosphorylates Cdc28, the cyclin-dependent kinase (CDK) governing the cell cycle, as well as Kin28, Bur1 and Ctk1, CDKs required for the transcription process performed by RNA polymerase II (RNA Pol II). Using genetic methods, we found that Cak1 genetically interacts with Paf1 and Ctr9, two components...

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Source

Identifiers

PMID: 16362371
DOI: 10.1007/s00438-005-0071-y

Genes

PAF1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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