Article
A role for fission yeast Rab GTPase Ypt7p in sporulation.
Cell structure and function - 1 Jan 2005
Kashiwazaki Jun, Nakamura Taro, Iwaki Tomoko, Takegawa Kaoru, Shimoda Chikashi
Abstract excerpt
Ypt7p, a fission yeast (Schizosaccharomyces pombe) homologue of Rab7 GTPase, mediates fusion of endosomes to vacuoles and homotypic vacuole fusion. Here, we report that Ypt7p plays important roles in sporulation. Most ypt7Delta asci produced less than four spores, which were apparently immature and germinated at low frequency. Furthermore, ypt7Delta cells were defective in development of the forespore membranes....
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