Article
Autophagy-deficient Schizosaccharomyces pombe mutants undergo partial sporulation during nitrogen starvation.
Microbiology (Reading, England) - 1 Dec 2009
Mukaiyama Hiroyuki, Kajiwara Shiro, Hosomi Akira, Giga-Hama Yuko, Tanaka Naotaka, Nakamura Taro, Takegawa Kaoru
Abstract excerpt
Autophagy is triggered when organisms sense radical environmental changes, including nutritional starvation. During autophagy, cytoplasmic components, including organelles, are enclosed within autophagosomes and are degraded upon lysosome-vacuole fusion. In this study, we show that processing of GFP-tagged Atg8 can serve as a marker for autophagy in the fission yeast Schizosaccharomyces pombe. Using this marker,...
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