Article
Involvement of Ypt7p, a small GTPase, in traffic from late endosome to the vacuole in yeast.
Journal of cell science - 1 Nov 1993
Schimmöller F, Riezman H
Abstract excerpt
The YPT7 gene encodes the Saccharomyces cerevisiae homolog of mammalian rab7 protein. Data obtained from studies on a delta ypt7 mutant suggested that Ypt7p is involved in the endocytic pathway in yeast (Wichmann et al., Cell 71, 1131-1142, 1992). We report here that endocytosed pheromone alpha-factor accumulates in late endosomes in delta ypt7 cells, indicating that Ypt7p is involved in the regulation of...
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