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Article

Fission yeast GPI inositol deacylase Bst1 regulates ER-Golgi transport and functions in late stages of cytokinesis.

Molecular biology of the cell - 1 Mar 2025

Ye Yanfang, Osmani Aysha H, Liu Zhen-Ru, Kern Addie, Wu Jian-Qiu

Abstract excerpt

The Munc13/UNC-13 family protein Ync13 is essential for septum integrity and cytokinesis in fission yeast. To further explore the mechanism of Ync13 functions, spontaneous suppressors of ync13 mutants, which can suppress the colony-formation defects and lysis phenotype of ync13 mutant cells, are isolated and characterized. One of the suppressor mutants, bst1-s27, shows defects in the cytokinetic contractile ring...

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Topics

Schizosaccharomyces
Cytokinesis
Endoplasmic Reticulum
Schizosaccharomyces pombe Proteins
Golgi Apparatus
Mutation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Protein Transport

Source

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Identifiers

PMID: 39813093
DOI: 10.1091/mbc.E24-08-0375
PMCID: PMC11974966

Genes

GPI

Provenance

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Fission yeast GPI inositol deacylase Bst1 regulates ER-Golgi transport and functions in late stages of cytokinesis.PMID 39813093Read ↗

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