Article
Cloning and characterization of a gene (avaA) from Aspergillus nidulans encoding a small GTPase involved in vacuolar biogenesis.
Gene - 29 May 2002
Ohsumi Keisuke, Arioka Manabu, Nakajima Harushi, Kitamoto Katsuhiko
Abstract excerpt
Several genes that play roles in vacuolar biogenesis and targeting of proteins to vacuoles have been characterized in Saccharomyces cerevisiae. Although the vacuole is one of the most prominent compartments, little is known about molecular mechanism of vacuolar biogenesis in filamentous fungi. Vam4/Ypt7p, a small GTPase of the Rab/Ypt family in S. cerevisiae, plays a vital role in homotypic vacuole fusion. We...
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