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Article

Epithelial and stromal genetic instability contributes to genesis of colorectal adenomas

14 Dec 2005

Abstract excerpt

BACKGROUND: Previously, we indicated that stromal genetic instability might contribute to tumorigenesis of both sporadic and ulcerative colitis associated colorectal adenocarcinomas. Considering the established adenoma-adenocarcinoma sequence, in this study we analysed genetic instability in colorectal adenoma cells and surrounding stroma. METHODS: In 164 colorectal tumours (34 hyperplastic polyps, 38 tubular...

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Identifiers

PMID: 16354798
DOI: 10.1136/gut.2005.079459

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