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Article

Mutations in Cog7 affect Golgi structure, meiotic cytokinesis and sperm development during Drosophila spermatogenesis.

Journal of cell science - 15 Nov 2012

Belloni Giorgio, Sechi Stefano, Riparbelli Maria Giovanna, Fuller Margaret T, Callaini Giuliano, Giansanti Maria Grazia

Abstract excerpt

The conserved oligomeric Golgi (COG) complex plays essential roles in Golgi function, vesicle trafficking and glycosylation. Deletions in the human COG7 gene are associated with a rare multisystemic congenital disorder of glycosylation that causes mortality within the first year of life. In this paper, we characterise the Drosophila orthologue of COG7 (Cog7). Loss-of-function Cog7 mutants are viable but male...

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Identifiers

PMID: 22946051
DOI: 10.1242/jcs.108878
PMCID: PMC7523631

Genes

COG7

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutations in Cog7 affect Golgi structure, meiotic cytokinesis and sperm development during Drosophila spermatogenesis.PMID 22946051Read ↗

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