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Article

Hepatic lipase and dyslipidemia: interactions among genetic variants, obesity, gender, and diet.

Journal of lipid research - 1 Jul 2003

Deeb Samir S, Zambon Alberto, Carr Molly C, Ayyobi Amir F, Brunzell John D

Abstract excerpt

Hepatic lipase (HL) plays a central role in LDL and HDL remodeling. High HL activity is associated with small, dense LDL particles and with reduced HDL2 cholesterol levels. HL activity is determined by an HL gene promoter polymorphism, by gender (lower in premenopausal women), and by visceral obe...

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Source

Identifiers

PMID: 12639974
DOI: 10.1194/jlr.R200017-JLR200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12639974-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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