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Article

Hyperandrogenism in POMCa-deficient zebrafish enhances somatic growth without increasing adiposity

20 Jun 2019

Abstract excerpt

The endocrine regulatory roles of the hypothalamic-pituitary-adrenocortical axis on anxiety-like behavior and metabolic status have been found throughout animal taxa. However, the precise effects of the balancing adrenal corticosteroid biosynthesis under the influence of adrenocorticotrophic hormone (ACTH), a pro-opiomelanocortin (POMC)-derived peptide, on animal energy expenditure and somatic growth remain...

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PMID: 31237951
DOI: 10.1093/jmcb/mjz053

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