Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RscA, a member of the MDR1 family of transporters, is repressed by CovR and required for growth of Streptococcus pyogenes under heat stress.

Journal of bacteriology - 1 Jan 2006

Dalton Tracy L, Collins Julie T, Barnett Timothy C, Scott June R

Abstract excerpt

The ability of Streptococcus pyogenes (group A streptococcus [GAS]) to respond to changes in environmental conditions is essential for this gram-positive organism to successfully cause disease in its human host. The two-component system CovRS controls expression of about 15% of the GAS genome either directly or indirectly. In most operons studied, CovR acts as a repressor. We previously linked CovRS to the GAS...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP Binding Cassette Transporter, Subfamily B, Member 1
Share to ATP-Binding Cassette Transporters

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

Share to Heat-Shock Response

Share to Hot Temperature

Share to Hydrogen-Ion Concentration

Share to Regulon

Share to Streptococcus pyogenes

Source

Open in PubMed Open full text

Identifiers

PMID: 16352823
DOI: 10.1128/JB.188.1.77-85.2006
PMCID: PMC1317578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RscA, a member of the MDR1 family of transporters, is repressed by CovR and required for growth of Streptococcus pyogenes under heat stress.PMID 16352823Read ↗

CovS inactivates CovR and is required for growth under conditions of general stress in Streptococcus pyogenes.Semantic proximity Read ↗

CovS inactivation reduces CovR promoter binding at diverse virulence factor encoding genes in group A StreptococcusSemantic proximity Read ↗

CovR-Controlled Global Regulation of Gene Expression in Streptococcus mutansSemantic proximity Read ↗

Mg(2+) signalling defines the group A streptococcal CsrRS (CovRS) regulon.Semantic proximity Read ↗

Constitutive activation of two-component systems reveals regulatory network interactions in Streptococcus agalactiae.Semantic proximity Read ↗

Signal transduction through CsrRS confers an invasive phenotype in group A Streptococcus.Semantic proximity Read ↗

Transcriptional analysis of the acid tolerance response in Streptococcus pneumoniaeSemantic proximity Read ↗

CovS Simultaneously Activates and Inhibits the CovR-Mediated Repression of Distinct Subsets of Group A <i>Streptococcus</i> Virulence Factor-Encoding GenesSemantic proximity Read ↗

Phosphatase activity of the control of virulence sensor kinase CovS is critical for the pathogenesis of group A streptococcusSemantic proximity Read ↗

Virulence control in group A Streptococcus by a two-component gene regulatory system: global expression profiling and in vivo infection modeling.Semantic proximity Read ↗

Characterization of the effect of the histidine kinase CovS on response regulator phosphorylation in group A Streptococcus.Semantic proximity Read ↗

CovS/CovR of group B streptococcus: a two‐component global regulatory system involved in virulenceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.