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Article

Cardiac metabolism in mice: tracer method developments and in vivo application revealing profound metabolic inflexibility in diabetes.

American journal of physiology. Endocrinology and metabolism - 1 May 2006

Oakes Nicholas D, Thalén Pia, Aasum Ellen, Edgley Amanda, Larsen Terje, Furler Stuart M, Ljung Bengt, Severson David

Abstract excerpt

Studies of cardiac fuel metabolism in mice have been almost exclusively conducted ex vivo. The major aim of this study was to assess in vivo plasma FFA and glucose utilization by the hearts of healthy control (db/+) and diabetic (db/db) mice, based on cardiac uptake of (R)-2-[9,10-(3)H]bromopalmitate ([3H]R-BrP) and 2-deoxy-D-[U-14C]glucose tracers. To obtain quantitative information about the evaluation of...

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PMID: 16352676
DOI: 10.1152/ajpendo.00233.2005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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