Article

Molecular and genetic mechanisms of myocardial insulin resistance in humans and mice

2011-01-01

Abstract excerpt

Patients with type 2 diabetes mellitus have a greatly increased risk of coronary artery disease and heart failure due to a number of factors such as insulin resistance, hyperglycaemia, arterial hypertension, and obesity. To study the changes seen in hearts of diabetic patients the aim of this project was to generate a clinically relevant diet-induced obese mouse model which could mimic these changes. Male C57BL/6...

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Literature Corpus work: 712244b6-6228-5658-85f0-c601b285b463
DOI: 10.25560/9123

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