Article
Genomic structure and genetic drift in C57BL/6 congenic metabolic mutant mice.
Molecular genetics and metabolism - 1 Nov 2013
Almodovar Alvin J O, Luther Rita J, Stonebrook Caron L, Wood Philip A
Abstract excerpt
We used a genome-wide single nucleotide polymorphism (SNP) approach to characterize the genomic structures of four representative C57BL/6 (B6) congenic mutant mouse lines to include the A) long-chain acyl-CoA dehydrogenase (Acadl), B) melanocortin 3 receptor (Mc3r), C) endothelial nitric oxide synthase (Nos3), and D) a replacement of mouse apolipoprotein E (Apoe) by human apolipoprotein E-2 (APOE2). We wanted to...
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