Article
Association analysis of polymorphisms in serotonin 1B receptor (HTR1B) gene with heroin addiction: a comparison of molecular and statistically estimated haplotypes.
Pharmacogenetics and genomics - 1 Jan 2006
Proudnikov Dmitri, LaForge K Steven, Hofflich Heather, Levenstien Mark, Gordon Derek, Barral Sandra, Ott Jurg, Kreek Mary Jeanne
Abstract excerpt
OBJECTIVES: 5-Hydroxytryptamine (serotonin)-1B receptors (HTR1B) may play an important role in psychiatric disorders and drug and alcohol dependence. In this study we report on genotype, molecular haplotype and statistically estimated haplotype analyses of previously identified polymorphisms in positions -261T>G, -161A>T, 129C>T, 861G>C and 1180A>G of the HTR1B gene in ethnically diverse populations...
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