Article
Adipogenic phenotype of hepatic stellate cells.
Alcoholism, clinical and experimental research - 1 Nov 2005
Tsukamoto Hide
Abstract excerpt
Transdifferentiation of hepatic stellate cells (HSC) constitutes a major cellular event in the genesis of alcoholic liver fibrosis and cirrhosis and molecular mechanisms underlying this process is incompletely understood. Our laboratory proposed several years ago that HSC quiescence requires the transcriptional program known to be integral to preadipocyte to adipocyte differentiation. In support of the...
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