Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Influence of polymorphism in DNA repair and defence genes on p53 mutations in bladder tumours.

Cancer letters - 8 Sept 2006

Ryk Charlotta, Kumar Rajiv, Sanyal Somali, de Verdier Petra J Berggren, Hemminki Kari, Larsson Per, Steineck Gunnar, Hou Sai-Mei

Abstract excerpt

We studied the effects of polymorphisms in nine genes involved in DNA repair and detoxification on occurrence and type of p53 mutation in 327 bladder cancer patients. The included polymorphisms are XPC(Lys939Gln), XPD(Lys751Gln), XPG(Asp1104His), XRCC1(Arg3999Gln), XRCC3(Thr241Met), NBS1(Glu185Gln), cyclin D1(Pro241Pro), MTHFR(Ala222Val and Glu429Ala) and NQO1(Arg139Trp and Pro187Ser). We found increased risk for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Repair
Share to XPC gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, p53

Share to Mutation

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Share to Polymorphism, Restriction Fragment Length

Share to Urinary Bladder Neoplasms

Source

Identifiers

PMID: 16343742
DOI: 10.1016/j.canlet.2005.10.025

Genes

NQO1
XPC
XRCC3
MTHFR
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Influence of polymorphism in DNA repair and defence genes on p53 mutations in bladder tumours.PMID 16343742Read ↗

Polymorphisms in DNA repair and metabolic genes in bladder cancer.Semantic proximity Read ↗

DNA repair gene polymorphisms and probability of p53 mutation in bladder cancer.Semantic proximity Read ↗

Interaction between polymorphisms of DNA repair genes significantly modulated bladder cancer risk.Semantic proximity Read ↗

Influence of GSTM1, GSTT1, GSTP1 and NAT2 genotypes on the p53 mutational spectrum in bladder tumours.Semantic proximity Read ↗

Study on bladder cancer susceptibility and genetic polymorphisms of XPC, XPG, and CYP in smokers and non-smokers.Semantic proximity Read ↗

Nucleotide excision repair gene polymorphisms may predict acute toxicity in patients treated with chemoradiotherapy for bladder cancer.Semantic proximity Read ↗

Genetic polymorphisms in the DNA repair genes XPD and XRCC1, p53 gene mutations and bladder cancer risk.Semantic proximity Read ↗

DNA repair gene polymorphisms and bladder cancer susceptibility in a Turkish population.Semantic proximity Read ↗

Polymorphisms/Haplotypes in DNA Repair Genes and Smoking: A Bladder Cancer Case-Control StudySemantic proximity Read ↗

DNA repair gene ERCC2, XPC, XRCC1, XRCC3 polymorphisms and associations with bladder cancer risk in a French cohort.Semantic proximity Read ↗

Polymorphisms in the XPC gene affect urinary bladder cancer risk: a case-control study, meta-analyses and trial sequential analyses.Semantic proximity Read ↗

Do DNA repair genes OGG1, XRCC3 and XRCC7 have an impact on susceptibility to bladder cancer in the North Indian population?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.