Article
Association between chronic hepatitis B virus infection and interleukin-10, tumor necrosis factor-alpha gene promoter polymorphisms.
Journal of gastroenterology and hepatology - 1 Jul 2006
Cheong Jae Youn, Cho Sung Won, Hwang Il Lan, Yoon Seung Kew, Lee June Hyuk, Park Choon Sik, Lee Jong Eun, Hahm Ki Baik, Kim Jin Hong
Abstract excerpt
BACKGROUND: The reasons for the viral persistence of hepatitis B virus infection (HBV) are unknown, but are probably related to host immune factors. Cytokines play a significant role in immune defense. The present study was undertaken to investigate the association between HBV infection and polymorphisms of tumor necrosis factor (TNF)-alpha and interleukin(IL)-10 gene promoter. METHODS: A total of 412 Korean...
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