Article
DNA sequence variation in the promoter region of the VEGF gene impacts VEGF gene expression and maximal oxygen consumption.
American journal of physiology. Heart and circulatory physiology - 1 May 2006
Prior Steven J, Hagberg James M, Paton Chad M, Douglass Larry W, Brown Michael D, McLenithan John C, Roth Stephen M
Abstract excerpt
In its role as an endothelial cell proliferation and migration factor, vascular endothelial growth factor (VEGF) can affect peripheral circulation and therefore impact maximal oxygen consumption (Vo2 max). Because of the role of VEGF, and because variation in the VEGF gene has the ability to alter VEGF gene expression and VEGF protein level, we hypothesized that VEGF gene polymorphisms are related to VEGF gene...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.